16-
Abdelwahab, N. S.; Farid, N. F.; Elagawany, M.; Abdelmomen, E. H. Efficient UPLC and CE methods for the simultaneous determination of azelastine Biomedical Chromatography, 2018, 32 (11), e4346. Click Here
17- Elagawany, M.; Hegazy, L.; Cao, F.; Donlin, M. J.; Rath, N.; Tavis, J.; Elgendy, B. Identification of 4-isopropyl–thiotropolone as a novel anti-microbial: regioselective synthesis, NMR characterization, and biological evaluation RSC Advances, 2018, 8 (52), 29967-29975 Click Here
19-Shahien, M.; Elagawany, M.; Sitaula, S.; Goher, S. S.; Burris, S. L.; Sanders, R.; Avdagic, A.; Billon, C.; Hegazy, L.; Burris, T. P.; Elgendy, B. Modulation of Estrogen-Related Receptors Subtype Selectivity: Conversion of an ERRβ/γ Selective Agonist to ERRα/β/γ Pan Agonists. Bioorg. Chem. 2020, 104079. Click Here
20-Elzahhar, P.A.; Abd El Wahab, S.M.; Elagawany, M.; Daabees, H.; Belal, A.S.F.; EL-Yazbi, A.F.; Eid, A.H.; Alaaeddine, R.; Hegazy, R.R.; Allam, R.M.; Helmy, M. W.; Elgendy, B.; Angeli, A.; El-Hawash, S. A.; Supuran, C. T. Expanding the anticancer potential of 1,2,3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases. Eur. J. Med. Chem. 2020, 200, 112439. Click Here
21-Ibrahim, T.S.; Seliem, I.A.; Panda, S.S.; Al-Mahmoudy, A.M.M.; Abdel-Samii, Z.K.M.; Alhakamy, N.A.; Asfour, H.Z.; Elagawany, M. An Efficient Greener Approach for N-acylation of Amines in Water Using Benzotriazole Chemistry. Molecules 2020, 25, 2501. Click Here
22- Ibrahim, T. S.; Bokhtia, R. M.; AL-Mahmoudy, A. M. M.; Taher, E. S.; AlAwadh, M. A.; Elagawany, M.; Abdel-Aal, E. H.; Panda, S.; Gouda, A. M.; Asfour, H. Z.; Alhakamy, N. A.; Youssif, B.G. M. Design, Synthesis and Biological Evaluation of Novel 5-((Substituted Quinolin-3-Yl/1-Naphthyl) Methylene)-3-Substituted Imidazolidin-2,4-Dione as HIV-1 Fusion Inhibitors. Bioorg. Chem. 2020, 99, 103782. Click Here
23-Saaed, W.; Elagawany, M.; Azab, M. M.; Amin, A. S.; Rath, N. P.; Hegazy, L.; Elgendy, B. Catalyst-and Organic Solvent-Free Synthesis, Structural, and Theoretical Studies of 1-Arylidenamino-2,4-Disubstituted-2-Imidazoline-5-Ones. Results Chem. 2020, 2, 100042. Click Here
24-Panda, S.S.; Girgis, A.S.; Mishra, B.B.; Elagawany, M.; Devarapalli, V.; Littlefield, W.F.; Samir, A.; Fayad, W.; Fawzy, N.G.; Srour, A.M.; Bokhtia, R.M. Synthesis, computational studies, antimycobacterial and antibacterial properties of pyrazinoic acid–isoniazid hybrid conjugates RSC Adv., 2019, 9, 20450. Click Here
25- Elagawany, M.; Hegazy, L.; Elgendy, B. Catalyst- and organic solvent-free synthesis of thioacids in water Tetrahedron Lett., 2019, 60, 2018. Click Here
26-Elagawany, M.; Fared, N. F.; Elgendy, B.; Abdelmomen, E. H.; Abdelwahab, N. S. Baclofen Impurities: Facile Synthesis and Novel Environmentally Benign Chromatographic Method for their Simultaneous Determination in Baclofen Biomed Chromatogr., 2019, 33, e4579. Click Here
27-Ghoneim, M. M.; Afifi, W. M.; Ibrahim, M.; Elagawany, M.; Khayat, M. T.; Aboutaleb, M. H.; Metwaly, A. M. Biological evaluation and molecular docking study of metabolites from Salvadora Persica L. Growing in Egypt Pharmacogn Mag., 2019, 15, 232. Click Here
28-Cao, F.; Orth, C.; Donlin, M. J.; Adegboyega, P.: Meyers, M. J.; Murelli, R. P.; Elagawany, M.; Elgendy, B.; Tavis, J. E. Synthesis and Evaluation of Troponoids as a New Class of Antibiotics ACS omega, 2018, 3, 15125. Click Here
29-Design, synthesis, and antihypertensive activity of new pyrimidine derivatives endowing new pharmacophores .
Ahmed M. Farghaly, Omaima M. AboulWafa, Yaseen A. M. Elshaier, Waleed A. Badawi, Haridy H. Haridy & Heba A. E. Mubarak Click Here
30-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study .
Omaima M.AboulWafa , Hoda M.G.Daabeesb, Waleed A.Badawi .Click Here
31- Development and validation of a highly sensitive second derivative synchronous fluorescence spectroscopic method for simultaneous determination of elbasvir and grazoprevir in pharmaceutical preparation and human plasma
Khalid Abdelsalam , ahmed elolemy , sherif ramzy , Ahmed Hussien Abdelazim , mohamed hassan , tahany mohamed , Zeinab Nasr , ghada mohammed and mohamed shahin Click Here
32- Febuxostat-based Amides and Some Derived Heterocycles Targeting Xanthine Oxidase and COX Inhibition. Synthesis, in vitro and in vivo Biological Evaluation, Molecular Modeling. Click Here
Aya Y Rashad, Shaymaa E Kassab, Hoda G Daabees, Ahmed E Abdel Moneim, Sherif AF Rostom
33-Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity. Click Here
Mahmoud A. Ragab, Mohamed Elagawany, Hoda Daabees, Al-Shaimaa F. Ahmed, Eman M. Awad, Cyrielle Billonc, Bahaa Elgendy, Khaled A. M. Abouzid, Shaymaa E. Kassab
34- New functionalized 6-thienylpyrimidine-5-carbonitriles as antiproliferative agents against human breast cancer cells. Click Here
Omaima M. AboulWafa.; Hoda M. G. Daabees.; Ali Hammad| Waleed A. Badawi
35-Design, synthesis and docking studies of new hydrazinyl-thiazole derivatives as anticancer and antimicrobial agents Click Here
Abeer M. El-Naggar.; Alaa Zidan.; Eslam B. Elkaeed.; Mohammed S. Taghour.; Waleed A. Badawi
36- Development and comprehensive greenness assessment for MEKC and HPTLC methods for simultaneous estimation of sertaconazole with two co-formulated preservatives in pharmaceutical dosage forms. Clik Here
Haydi Saher Elbordiny Sohila Mohamed Elonsy Hoda Gamal eldin .Daabees Tarek Saied Belal
37- Sustainable quantitative determination of allopurinol in fixed dose combinations with benzbromarone and thioctic acid by capillary zone electrophoresis and spectrophotometry: Validation, greenness and whiteness studies .Click Here
Haydi Saher Elbordiny Sohila Mohamed Elonsy Hoda Gamal eldin .Daabees Tarek Saied Belal
38- Design and Synthesis of Novel Quinazolinone-Based Oxobutanenitrile Derivatives as Antiproliferative Agents Targeting Human Breast Cancer. Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents), 22(12), 2310-2326. Click Here
AboulWafa, O. M., Daabees, H. M. G. E. D., & Ezz-ElDien, E. S. (2022).
39- Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme Click Here
Nada Hassan Azmy El-Dershaby, Soad Abdel Hamid El-Hawash, Shaymaa Emam Kassab, Hoda Mohamed Gamal Eldin Daabees, Ahmed Esmat Abdel Moneim, Ibrahim Ashraf Abdelwahab, Mohammad Mahmoud Abd-Alhaseeb, Mostafa Mohamed Mahmoud El-Miligy.
40- Rational Design and Synthesis of New Selective COX-2 Inhibitors with In Vivo PGE2-Lowering Activity by Tethering Benzenesulfonamide and 1,2,3-Triazole Pharmacophores to Some NSAIDs Click Here
Nada Hassan Azmy El-Dershaby, Soad Abdel Hamid El-Hawash, Shaymaa Emam Kassab, Hoda Mohamed Gamal Eldin Daabees, Ahmed Esmat Abdel Moneim, Mostafa Mohamed Mahmoud El-Miligy.
41-4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments Click Here
Mahmoud A. Ragab, Wagdy M. Eldehna, Alessio Nocentini, Alessandro Bonardi, Hazem E. Okda, Bahaa Elgendy, Tarek S. Ibrahim, Mohammad M. Abd-Alhaseeb, Paola Gratteri, Claudiu T. Supuran, Ahmed A. Al-Karmalawy, Mohamed Elagawany.
42-Identification of new 4-(6-oxopyridazin-1-yl)benzene-sulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and Modelling insights Click
Waleed A. Badawi, Mahmoud Rashed, Alessio Nocentini, Alessandro Bonardi, Mohammad M. Abd-Alhaseeb, Sara T. Al-Rashood, Giri Babu Veerakanellore, Taghreed A. Majrashi, Eslam B. Elkaeed, Bahaa Elgendyj, Paola Gratteri , Claudiu T. Supuran, Wagdy M. Eldehnak and Mohamed Elagawany
43- Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines Click Here
Waleed A. Badawi, Mohamed Samir, Hazem M. Fathy, Tarek M. Okda,
Mohamed H. Noureldin, Gamal M.K. Atwa, Omaima M. AboulWafa
44- Towards the Development of Dual Hypouricemic and Anti-inflammatory Candidates: Design, Synthesis, Stability Studies and Biological Evaluation of Some Mutual Ester Prodrugs of Febuxostat-NSAIDs Click Here
Aya Y. Rashad, Hoda G. Daabees, Mohamed Elagawany, Mohamed Shahin, Ahmed E. Abdel Moneim, Sherif A.F. Rostom
45- Implementation of two sustainable chromatographic methods for the simultaneous micro-quantitation and impurity profiling of metformin and rosuvastatin in recently approved fixed dose pills: Greenness and whiteness studies. Clcik Here
Haydi S. Elbordiny a, Sohila M. Elonsy b, Hoda G. Daabees a, Tarek S. Belal c
46- Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies Click Here
Authors
Ahmed A Al-Karmalawy, Dalia S El-Gamil, Rabeh El-Shesheny, Marwa Sharaky, Radwan Alnajjar, Omnia Kutkat, Yassmin Moatasim, Mohamed Elagawany, Sara T Al-Rashood, Faizah A Binjubair, Wagdy M Eldehna, Ayman M Noreddin, Mohamed Y Zakaria
47- Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease Click here
Authors
Mohamed Elagawany, Ayman Abo Elmaaty, Ahmed Mostafa, Noura M Abo Shama, Eman Y Santali, Bahaa Elgendy, Ahmed A Al-Karmalawy
48- Design, Synthesis and Antitumor Activity of Novel Dispiro [oxindole-cyclohexanone]-pyrrolidines Click Here
Authors
Magy Gouda, Majed Bawzeer, Lamees Hegazy, Mohamed Azab, Mohamed Elagawany, Mostafa Rateb, Mohammed Yaseen, Bahaa Elgendy
49-Green “turn‑off” luminescent nanosensors for the sensitive determination of desperately fluorescent antibacterial antiviral agent and its metabolite in various matrices Click Here
Hadil M. Elbardisy, Mai M. Elnaggar, Tarek S. Belal, Mahmoud A. Ragab, Amira F. El‑Yazbi
50- A New Avenue for Enhanced Treatment of Hyperuricemia and Oxidative Stress: Design, Synthesis and Biological Evaluation of Some Novel Mutual Prodrugs Involving Febuxostat Conjugated with Different Antioxidants Click Here
Aya Y. Rashad, Hoda G. Daabees, Mohamed Elagawany, Mohamed Shahin, Ahmed E. Abdel Moneim, Sherif A.F. Rostom
51- Development of a sustainable multianalyte MEKC method for quantitation of the antihyperlipidemic drugs ezetimibe together with three statins. Greenness and whiteness appraisal studies. Click Here
Haydi S. Elbordiny a, Sohila M. Elonsy b, Hoda G. Daabees a, Tarek S. Belal c
52- Tailoring two white chromatographic platforms for simultaneous estimation of ritonavir-boosted nirmatrelvir in their novel pills: degradation, validation, and environmental impact studies. Click Here
Haydi S. Elbordiny*a, Nourah Z. Alzoman b, Hadir M. Maher c and Sara I. Aboras c
53- Camptothecin structure simplification elaborated new imidazo[2,1-b]quinazoline derivative as a human topoisomerase I inhibitor with efficacy against bone cancer cells and colon adenocarcinoma Click Here
Ahmed I. Khodair a,**, Salwa M. El-Hallouty b, Brittnee Cagle-Whitec, May H. Abdel Azizc, Mahmoud Kh. Hanafy b,d, Samar Mowafy e, Nadia M. Hamdy f,***, Shaymaa E. Kassabg,*
54- Dual inhibition strategy addressing hyperuricemia and oxidative stress: design, biological evaluation and stability studies of febuxostat-probenecid mutual prodrug Click Here
Aya Y. Rashad, Hoda G. Daabees, Mohamed Elagawany, Mohamed Shahin, Ahmed E. Abdel Moneim, Maram Y. Marei, Sherif A. F. Rostom
55- Developing new anticancer agents: Design, synthesis, biological evaluation and in silico study of several functionalized pyrimidine-5-carbonitriles as small molecules modulators targeting breast cancer Click Here
Waleed A. Badawi, Tarek M. Okda, Shrouk M. Abd El Wahab, Eman S. Ezz-ElDien, Omaima M. AboulWafa