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ملخص:
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This thesis includes three main chapters and ends with
a list of references
The first chapter covers the most up to date literature for the reaction of erythro—2,3-dibromoketones with different nucleophiles and the postulated mechanisms for these reactions
The second chapter is divided into two parts:
The first part describes the method of preparation of trans— 1,3—diaryl—2-propenones ia—i and their bromination in
chloroform which gave the corresponding erythro—2,3—dibromo— 1,3-diaryl—1--propanone ,ai
p-Y-- C6
‘6 H4—X—p
0
II
C—C6 H4-Y—p
_____ ythro
trons-21 a-j
a-d, X = H; a, Y = H; b, Y = CH3 C, Y = Cl; d, Y = Br
e-i, Y = H; e, X = CH3 f, X = OCH3 g, X = NO2 h, X = Cl; 1, X = Br
The preparation of some of 1,3—diaryl—2—bromo—2—propen— ones 3 was also described as they supposed to be formed as intermediates during the reaction of erythro—2, 3—dibromo— ketones2a..j with different nucleophiles.
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